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RIG-I Is Required for the Inhibition of Measles Virus by Retinoids

Vitamin A can significantly decrease measles-associated morbidity and mortality. Vitamin A can inhibit the replication of measles virus (MeV) in vitro through an RARα- and type I interferon (IFN)-dependent mechanism. Retinoid-induced gene I (RIG-I) expression is induced by retinoids, activated by Me...

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Detalles Bibliográficos
Autores principales: Soye, Kaitlin J., Trottier, Claire, Richardson, Chris D., Ward, Brian J., Miller, Wilson H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139622/
https://www.ncbi.nlm.nih.gov/pubmed/21811588
http://dx.doi.org/10.1371/journal.pone.0022323