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Synthesis and Investigation of a Radioiodinated F3 Peptide Analog as a SPECT Tumor Imaging Radioligand

A radioiodinated derivative of the tumor-homing F3 peptide, (N-(2-{3-[(125)I]Iodobenzoyl}aminoethyl)maleimide-F3Cys peptide, [(125)I]IBMF3 was developed for investigation as a SPECT tumor imaging radioligand. For this purpose, we custom synthesized a modified F3 peptide analog (F3Cys) incorporating...

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Detalles Bibliográficos
Autores principales: Bhojani, Mahaveer S., Ranga, Rajesh, Luker, Gary D., Rehemtulla, Alnawaz, Ross, Brian D., Van Dort, Marcian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139646/
https://www.ncbi.nlm.nih.gov/pubmed/21811604
http://dx.doi.org/10.1371/journal.pone.0022418