Cargando…

Chronic HO-1 Induction with Cobalt Protoporphyrin (CoPP) Treatment Increases Oxygen Consumption, Activity, Heat Production and Lowers Body Weight in Obese Melanocortin-4 Receptor Deficient Mice

OBJECTIVE: Heme oxygenase-1 induction (HO-1) elicits chronic weight loss in several rodent models of obesity. Despite these findings, the mechanism by which HO-1 induction reduces body weight is unclear. Chronic HO-1 induction does not alter food intake suggesting other mechanisms such as increases...

Descripción completa

Detalles Bibliográficos
Autores principales: Csongradi, Eva, doCarmo, Jussara M., Dubinion, John H., Vera, Trinity, Stec, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139690/
https://www.ncbi.nlm.nih.gov/pubmed/21467998
http://dx.doi.org/10.1038/ijo.2011.78