B-Cell Gene Therapy for Tolerance Induction: Host but Not Donor B-Cell Derived IL-10 is Necessary for Tolerance

Genetically modified B cells are excellent tolerogenic antigen-presenting cells (APCs) in multiple models of autoimmunity. However, the mechanisms of action are still not completely understood. In our models, we generate antigen-specific tolerogenic B cells by transducing naïve or primed B cells wit...

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Detalles Bibliográficos
Autores principales: Su, Yan, Zhang, Ai-Hong, Noben-Trauth, Nancy, Scott, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139928/
https://www.ncbi.nlm.nih.gov/pubmed/21811487
http://dx.doi.org/10.3389/fmicb.2011.00154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139928/
https://www.ncbi.nlm.nih.gov/pubmed/21811487
http://dx.doi.org/10.3389/fmicb.2011.00154

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