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A Scalable Gene Synthesis Platform Using High-Fidelity DNA Microchips

Development of cheap, high-throughput, and reliable gene synthesis methods will broadly stimulate progress in biology and biotechnology1. Currently, the reliance on column-synthesized oligonucleotides as a source of DNA limits further cost reductions in gene synthesis2. Oligonucleotides from DNA mic...

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Detalles Bibliográficos
Autores principales: Kosuri, Sriram, Eroshenko, Nikolai, LeProust, Emily, Super, Michael, Way, Jeffrey, Li, Jin Billy, Church, George M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139991/
https://www.ncbi.nlm.nih.gov/pubmed/21113165
http://dx.doi.org/10.1038/nbt.1716