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A Scalable Gene Synthesis Platform Using High-Fidelity DNA Microchips
Development of cheap, high-throughput, and reliable gene synthesis methods will broadly stimulate progress in biology and biotechnology1. Currently, the reliance on column-synthesized oligonucleotides as a source of DNA limits further cost reductions in gene synthesis2. Oligonucleotides from DNA mic...
Autores principales: | Kosuri, Sriram, Eroshenko, Nikolai, LeProust, Emily, Super, Michael, Way, Jeffrey, Li, Jin Billy, Church, George M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139991/ https://www.ncbi.nlm.nih.gov/pubmed/21113165 http://dx.doi.org/10.1038/nbt.1716 |
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