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Interferon-γ links UV to melanocyte activation and promotes melanomagenesis

Cutaneous malignant melanoma is a highly aggressive and frequently chemoresistant cancer, whose incidence continues to rise. Epidemiological studies reveal that the major etiological melanoma risk factor is ultraviolet (UV) solar radiation, with the highest risk associated with intermittent burning...

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Detalles Bibliográficos
Autores principales: Zaidi, M. Raza, Davis, Sean, Noonan, Frances P., Graff-Cherry, Cari, Hawley, Teresa S., Walker, Robert L., Feigenbaum, Lionel, Fuchs, Elaine, Lyakh, Lyudmila, Young, Howard A., Hornyak, Thomas J., Arnheiter, Heinz, Trinchieri, Giorgio, Meltzer, Paul S., De Fabo, Edward C., Merlino, Glenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140101/
https://www.ncbi.nlm.nih.gov/pubmed/21248750
http://dx.doi.org/10.1038/nature09666