Glutamine Triggers and Potentiates Glucagon-Like Peptide-1 Secretion by Raising Cytosolic Ca(2+) and cAMP

L-glutamine stimulates glucagon-like peptide 1 (GLP-1) secretion in human subjects and cell lines. As recent advances have enabled the study of primary GLP-1–releasing L cells, this study aimed to characterize glutamine-sensing pathways in native murine L cells. L cells were identified using transge...

Descripción completa

Detalles Bibliográficos
Autores principales: Tolhurst, Gwen, Zheng, Yue, Parker, Helen E., Habib, Abdella M., Reimann, Frank, Gribble, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2011
Materias:
Diabetes-Insulin-Glucagon-Gastrointestinal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140224/
https://www.ncbi.nlm.nih.gov/pubmed/21209017
http://dx.doi.org/10.1210/en.2010-0956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140224/
https://www.ncbi.nlm.nih.gov/pubmed/21209017
http://dx.doi.org/10.1210/en.2010-0956

Ejemplares similares