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Glutamine Triggers and Potentiates Glucagon-Like Peptide-1 Secretion by Raising Cytosolic Ca(2+) and cAMP

L-glutamine stimulates glucagon-like peptide 1 (GLP-1) secretion in human subjects and cell lines. As recent advances have enabled the study of primary GLP-1–releasing L cells, this study aimed to characterize glutamine-sensing pathways in native murine L cells. L cells were identified using transge...

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Detalles Bibliográficos
Autores principales:	Tolhurst, Gwen, Zheng, Yue, Parker, Helen E., Habib, Abdella M., Reimann, Frank, Gribble, Fiona M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2011
Materias:	Diabetes-Insulin-Glucagon-Gastrointestinal
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140224/ https://www.ncbi.nlm.nih.gov/pubmed/21209017 http://dx.doi.org/10.1210/en.2010-0956

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