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A biological pathway linking inflammation and depression: activation of indoleamine 2,3-dioxygenase

This article highlights the evidence linking depression to increased inflammatory drive and explores putative mechanisms for the association by reviewing both preclinical and clinical literature. The enzyme indoleamine 2,3-dioxygenase is induced by proinflammatory cytokines and may form a link betwe...

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Detalles Bibliográficos
Autores principales: Christmas, David M, Potokar, JP, Davies, Simon JC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140295/
https://www.ncbi.nlm.nih.gov/pubmed/21792309
http://dx.doi.org/10.2147/NDT.S17573