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A biological pathway linking inflammation and depression: activation of indoleamine 2,3-dioxygenase
This article highlights the evidence linking depression to increased inflammatory drive and explores putative mechanisms for the association by reviewing both preclinical and clinical literature. The enzyme indoleamine 2,3-dioxygenase is induced by proinflammatory cytokines and may form a link betwe...
Autores principales: | Christmas, David M, Potokar, JP, Davies, Simon JC |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140295/ https://www.ncbi.nlm.nih.gov/pubmed/21792309 http://dx.doi.org/10.2147/NDT.S17573 |
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