Functional Evolution of BRCT Domains from Binding DNA to Protein

The BRCT domain (BRCA1 C-terminal domain) is an important signaling and protein targeting motif in the DNA damage response system. The BRCT domain, which mainly occurs as a singleton (single BRCT) or tandem pair (double BRCT), contains a phosphate-binding pocket that can bind the phosphate from eith...

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Detalles Bibliográficos
Autores principales: Sheng, Zi-Zhang, Zhao, Yu-Qi, Huang, Jing-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140412/
https://www.ncbi.nlm.nih.gov/pubmed/21814458
http://dx.doi.org/10.4137/EBO.S7084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140412/
https://www.ncbi.nlm.nih.gov/pubmed/21814458
http://dx.doi.org/10.4137/EBO.S7084

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