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Functional Evolution of BRCT Domains from Binding DNA to Protein

The BRCT domain (BRCA1 C-terminal domain) is an important signaling and protein targeting motif in the DNA damage response system. The BRCT domain, which mainly occurs as a singleton (single BRCT) or tandem pair (double BRCT), contains a phosphate-binding pocket that can bind the phosphate from eith...

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Detalles Bibliográficos
Autores principales:	Sheng, Zi-Zhang, Zhao, Yu-Qi, Huang, Jing-Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Libertas Academica 2011
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140412/ https://www.ncbi.nlm.nih.gov/pubmed/21814458 http://dx.doi.org/10.4137/EBO.S7084

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