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Comprehensive Analysis of 5-Aminolevulinic Acid Dehydrogenase (ALAD) Variants and Renal Cell Carcinoma Risk among Individuals Exposed to Lead

BACKGROUND: Epidemiologic studies are reporting associations between lead exposure and human cancers. A polymorphism in the 5-aminolevulinic acid dehydratase (ALAD) gene affects lead toxicokinetics and may modify the adverse effects of lead. METHODS: The objective of this study was to evaluate singl...

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Detalles Bibliográficos
Autores principales: van Bemmel, Dana M., Boffetta, Paolo, Liao, Linda M., Berndt, Sonja I., Menashe, Idan, Yeager, Meredith, Chanock, Stephen, Karami, Sara, Zaridze, David, Matteev, Vsevolod, Janout, Vladimir, Kollarova, Hellena, Bencko, Vladimir, Navratilova, Marie, Szeszenia-Dabrowska, Neonilia, Mates, Dana, Slamova, Alena, Rothman, Nathaniel, Han, Summer S., Rosenberg, Philip S., Brennan, Paul, Chow, Wong-Ho, Moore, Lee E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140467/
https://www.ncbi.nlm.nih.gov/pubmed/21799727
http://dx.doi.org/10.1371/journal.pone.0020432