p16(INK4A) Positively Regulates Cyclin D1 and E2F1 through Negative Control of AUF1

BACKGROUND: The cyclin-D/CDK4,6/p16(INK4a)/pRB/E2F pathway, a key regulator of the critical G1 to S phase transition of the cell cycle, is universally disrupted in human cancer. However, the precise function of the different members of this pathway and their functional interplay are still not well d...

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Detalles Bibliográficos
Autores principales: Al-Khalaf, Huda H., Colak, Dilek, Al-Saif, Maher, Al-Bakheet, Albandary, Hendrayani, Siti-Faujiah, Al-Yousef, Nujoud, Kaya, Namik, Khabar, Khalid S., Aboussekhra, Abdelilah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140473/
https://www.ncbi.nlm.nih.gov/pubmed/21799732
http://dx.doi.org/10.1371/journal.pone.0021111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140473/
https://www.ncbi.nlm.nih.gov/pubmed/21799732
http://dx.doi.org/10.1371/journal.pone.0021111

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