Autotaxin and LPA Receptors Represent Potential Molecular Targets for the Radiosensitization of Murine Glioma through Effects on Tumor Vasculature

Despite wide margins and high dose irradiation, unresectable malignant glioma (MG) is less responsive to radiation and is uniformly fatal. We previously found that cytosolic phospholipase A2 (cPLA(2)) is a molecular target for radiosensitizing cancer through the vascular endothelium. Autotaxin (ATX)...

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Detalles Bibliográficos
Autores principales: Schleicher, Stephen M., Thotala, Dinesh K., Linkous, Amanda G., Hu, Rong, Leahy, Kathleen M., Yazlovitskaya, Eugenia M., Hallahan, Dennis E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140496/
https://www.ncbi.nlm.nih.gov/pubmed/21799791
http://dx.doi.org/10.1371/journal.pone.0022182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140496/
https://www.ncbi.nlm.nih.gov/pubmed/21799791
http://dx.doi.org/10.1371/journal.pone.0022182

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