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Autotaxin and LPA Receptors Represent Potential Molecular Targets for the Radiosensitization of Murine Glioma through Effects on Tumor Vasculature
Despite wide margins and high dose irradiation, unresectable malignant glioma (MG) is less responsive to radiation and is uniformly fatal. We previously found that cytosolic phospholipase A2 (cPLA(2)) is a molecular target for radiosensitizing cancer through the vascular endothelium. Autotaxin (ATX)...
Autores principales: | Schleicher, Stephen M., Thotala, Dinesh K., Linkous, Amanda G., Hu, Rong, Leahy, Kathleen M., Yazlovitskaya, Eugenia M., Hallahan, Dennis E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140496/ https://www.ncbi.nlm.nih.gov/pubmed/21799791 http://dx.doi.org/10.1371/journal.pone.0022182 |
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