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Strong Association of 677 C>T Substitution in the MTHFR Gene with Male Infertility - A Study on an Indian Population and a Meta-Analysis

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) is an important enzyme of folate and methionine metabolism, making it crucial for DNA synthesis and methylation. The objective of this study was to analyze MTHFR gene 677C>T polymorphism in infertile male individuals from North India, follow...

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Detalles Bibliográficos
Autores principales: Gupta, Nishi, Gupta, Saraswati, Dama, Madhukar, David, Archana, Khanna, Geeta, Khanna, Anil, Rajender, Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140509/
https://www.ncbi.nlm.nih.gov/pubmed/21799811
http://dx.doi.org/10.1371/journal.pone.0022277