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NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation

Cancer cell molecular mimicry of stem cells (SC) imbues neoplastic cells with enhanced proliferative and renewal capacities. In support, numerous mediators of SC self-renewal have been evinced to exhibit oncogenic potential. We have recently reported that shRNA-mediated knockdown of the embryonic st...

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Detalles Bibliográficos
Autores principales: Jeter, Collene R., Liu, Bigang, Liu, Xin, Chen, Xin, Liu, Can, Calhoun-Davis, Tammy, Repass, John, Zaehres, Holm, Shen, J. J., Tang, Dean G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140601/
https://www.ncbi.nlm.nih.gov/pubmed/21499299
http://dx.doi.org/10.1038/onc.2011.114