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Evaluation of CYP450 inhibitory effects and steady-state pharmacokinetics of genistein in combination with cholecalciferol and citrated zinc bisglycinate in postmenopausal women

BACKGROUND: The combination of genistein 27 mg, cholecalciferol 200 IU, citrated zinc bisglycinate (4 mg elemental zinc) 20 mg per capsule in Fosteum(®), a prescription medical food regulated by the FDA and indicated for the dietary management of osteopenia and osteoporosis, was tested for drug inte...

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Detalles Bibliográficos
Autores principales: Burnett, Bruce P, Pillai, Lakshmi, Bitto, Alessandra, Squadrito, Francesco, Levy, Robert M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140810/
https://www.ncbi.nlm.nih.gov/pubmed/21792336
http://dx.doi.org/10.2147/IJWH.S19309