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Reduced dosage of the modifiers of epigenetic reprogramming Dnmt1, Dnmt3L, SmcHD1 and Foxo3a has no detectable effect on mouse telomere length in vivo

Studies carried out in cultured cells have implicated modifiers of epigenetic reprogramming in the regulation of telomere length, reporting elongation in cells that were null for DNA methyltransferase DNA methyltransferase 1 (Dnmt1), both de novo DNA methyltransferases, Dnmt3a and Dnmt3b or various...

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Detalles Bibliográficos
Autores principales: Roberts, Amity R., Blewitt, Marnie E., Youngson, Neil A., Whitelaw, Emma, Chong, Suyinn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140923/
https://www.ncbi.nlm.nih.gov/pubmed/21553025
http://dx.doi.org/10.1007/s00412-011-0318-9