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Simvastatin improves learning and memory in control but not in olfactory bulbectomized rats

RATIONALE: Olfactory bulbectomy (OBX) in a laboratory rodent leads to numerous behavioral deficits and involves cognitive and motor changes that are used to model major depression, but may also be a valuable tool in the study of neurodegenerative disorders like Alzheimer’s disease. OBJECTIVES: This...

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Detalles Bibliográficos
Autores principales: Douma, Tessa N., Borre, Yuliya, Hendriksen, Hendrikus, Olivier, Berend, Oosting, Ronald S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140942/
https://www.ncbi.nlm.nih.gov/pubmed/21384104
http://dx.doi.org/10.1007/s00213-011-2245-0