Use of MicroRNA Let-7 to Control the Replication Specificity of Oncolytic Adenovirus in Hepatocellular Carcinoma Cells

Highly selective therapy for hepatocellular carcinoma (HCC) remains an unmet medical need. In present study, we found that the tumor suppressor microRNA, let-7 was significantly downregulated in a proportion of primary HCC tissues (12 of 33, 36.4%) and HCC cell lines. In line with this finding, we h...

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Detalles Bibliográficos
Autores principales: Jin, Huajun, Lv, Saiqun, Yang, Jiahe, Wang, Xiaoning, Hu, Huanzhang, Su, Changqing, Zhou, Chengliang, Li, Jiang, Huang, Yao, Li, Linfang, Liu, Xinyuan, Wu, Mengchao, Qian, Qijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140979/
https://www.ncbi.nlm.nih.gov/pubmed/21814544
http://dx.doi.org/10.1371/journal.pone.0021307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140979/
https://www.ncbi.nlm.nih.gov/pubmed/21814544
http://dx.doi.org/10.1371/journal.pone.0021307

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