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Replication and Explorations of High-Order Epistasis Using a Large Advanced Intercross Line Pedigree
Dissection of the genetic architecture of complex traits persists as a major challenge in biology; despite considerable efforts, much remains unclear including the role and importance of genetic interactions. This study provides empirical evidence for a strong and persistent contribution of both sec...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140984/ https://www.ncbi.nlm.nih.gov/pubmed/21814519 http://dx.doi.org/10.1371/journal.pgen.1002180 |