Defective CFTR Expression and Function Are Detectable in Blood Monocytes: Development of a New Blood Test for Cystic Fibrosis

BACKGROUND: Evaluation of cystic fibrosis transmembrane conductance regulator (CFTR) functional activity to assess new therapies and define diagnosis of cystic fibrosis (CF) is cumbersome. It is known that leukocytes express detectable levels of CFTR but the molecule has not been characterized in th...

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Detalles Bibliográficos
Autores principales: Sorio, Claudio, Buffelli, Mario, Angiari, Chiara, Ettorre, Michele, Johansson, Jan, Vezzalini, Marzia, Viviani, Laura, Ricciardi, Mario, Verzè, Genny, Assael, Baroukh Maurice, Melotti, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141019/
https://www.ncbi.nlm.nih.gov/pubmed/21811577
http://dx.doi.org/10.1371/journal.pone.0022212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141019/
https://www.ncbi.nlm.nih.gov/pubmed/21811577
http://dx.doi.org/10.1371/journal.pone.0022212

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