The Action Mechanism of the Myc Inhibitor Termed Omomyc May Give Clues on How to Target Myc for Cancer Therapy

Recent evidence points to Myc – a multifaceted bHLHZip transcription factor deregulated in the majority of human cancers – as a priority target for therapy. How to target Myc is less clear, given its involvement in a variety of key functions in healthy cells. Here we report on the action mechanism o...

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Detalles Bibliográficos
Autores principales: Savino, Mauro, Annibali, Daniela, Carucci, Nicoletta, Favuzzi, Emilia, Cole, Michael D., Evan, Gerard I., Soucek, Laura, Nasi, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141027/
https://www.ncbi.nlm.nih.gov/pubmed/21811581
http://dx.doi.org/10.1371/journal.pone.0022284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141027/
https://www.ncbi.nlm.nih.gov/pubmed/21811581
http://dx.doi.org/10.1371/journal.pone.0022284

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