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Crystallography of a Lewis-Binding Norovirus, Elucidation of Strain-Specificity to the Polymorphic Human Histo-Blood Group Antigens

Noroviruses, an important cause of acute gastroenteritis in humans, recognize the histo-blood group antigens (HBGAs) as host susceptible factors in a strain-specific manner. The crystal structures of the HBGA-binding interfaces of two A/B/H-binding noroviruses, the prototype Norwalk virus (GI.1) and...

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Detalles Bibliográficos
Autores principales: Chen, Yutao, Tan, Ming, Xia, Ming, Hao, Ning, Zhang, Xuejun C., Huang, Pengwei, Jiang, Xi, Li, Xuemei, Rao, Zihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141052/
https://www.ncbi.nlm.nih.gov/pubmed/21811409
http://dx.doi.org/10.1371/journal.ppat.1002152