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Evidence for the Complexity of MicroRNA-Mediated Regulation in Ovarian Cancer: A Systems Approach

MicroRNAs (miRNAs) are short (∼22 nucleotides) regulatory RNAs that can modulate gene expression and are aberrantly expressed in many diseases including cancer. Previous studies have shown that miRNAs inhibit the translation and facilitate the degradation of their targeted messenger RNAs (mRNAs) mak...

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Detalles Bibliográficos
Autores principales: Shahab, Shubin W., Matyunina, Lilya V., Mezencev, Roman, Walker, L. DeEtte, Bowen, Nathan J., Benigno, Benedict B., McDonald, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141058/
https://www.ncbi.nlm.nih.gov/pubmed/21811625
http://dx.doi.org/10.1371/journal.pone.0022508