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Acute Vhl Gene Inactivation Induces Cardiac HIF-Dependent Erythropoietin Gene Expression

Von Hippel Lindau (Vhl) gene inactivation results in embryonic lethality. The consequences of its inactivation in adult mice, and of the ensuing activation of the hypoxia-inducible factors (HIFs), have been explored mainly in a tissue-specific manner. This mid-gestation lethality can be also circumv...

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Detalles Bibliográficos
Autores principales: Miró-Murillo, Marta, Elorza, Ainara, Soro-Arnáiz, Inés, Albacete-Albacete, Lucas, Ordoñez, Angel, Balsa, Eduardo, Vara-Vega, Alicia, Vázquez, Silvia, Fuertes, Esther, Fernández-Criado, Carmen, Landázuri, Manuel O., Aragonés, Julián
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141062/
https://www.ncbi.nlm.nih.gov/pubmed/21811636
http://dx.doi.org/10.1371/journal.pone.0022589