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Deficiency in trefoil factor 1 (TFF1) increases tumorigenicity of human breast cancer cells and mammary tumor development in TFF1-knockout mice

Although trefoil factor 1 (TFF1; previously named pS2) is abnormally expressed in about 50% of human breast tumors, its physiopathological role in this disease has been poorly studied. Moreover, controversial data have been reported. TFF1 function in the mammary gland therefore needs to be clarified...

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Detalles Bibliográficos
Autores principales: Buache, E, Etique, N, Alpy, F, Stoll, I, Muckensturm, M, Reina-San-Martin, B, Chenard, M P, Tomasetto, C, Rio, M C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141110/
https://www.ncbi.nlm.nih.gov/pubmed/21358676
http://dx.doi.org/10.1038/onc.2011.41