Direct measurement of DNA bending by type IIA topoisomerases: implications for non-equilibrium topology simplification

Type IIA topoisomerases modify DNA topology by passing one segment of duplex DNA (transfer or T–segment) through a transient double-strand break in a second segment of DNA (gate or G–segment) in an ATP-dependent reaction. Type IIA topoisomerases decatenate, unknot and relax supercoiled DNA to levels...

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Detalles Bibliográficos
Autores principales: Hardin, Ashley H., Sarkar, Susanta K., Seol, Yeonee, Liou, Grace F., Osheroff, Neil, Neuman, Keir C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141238/
https://www.ncbi.nlm.nih.gov/pubmed/21421557
http://dx.doi.org/10.1093/nar/gkr109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141238/
https://www.ncbi.nlm.nih.gov/pubmed/21421557
http://dx.doi.org/10.1093/nar/gkr109

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