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The alternative protein isoform NK2B, encoded by the vnd/NK-2 proneural gene, directly activates transcription and is expressed following the start of cells differentiation

NK-2 is a homeodomain protein essential for the development of the central nervous system in the Drosophila embryo. Here, we show that the vnd/NK-2 gene encodes an additional protein isoform (NK-2B) that differs from the known one (NK-2A) in its N-terminal domain. While NK-2A is a transcription repr...

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Detalles Bibliográficos
Autores principales: Stepchenko, Alexander G., Pankratova, Elizaveta V., Doronin, Semen A., Gulag, Pavel V., Georgieva, Sofia G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141242/
https://www.ncbi.nlm.nih.gov/pubmed/21422076
http://dx.doi.org/10.1093/nar/gkr121