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The alternative protein isoform NK2B, encoded by the vnd/NK-2 proneural gene, directly activates transcription and is expressed following the start of cells differentiation
NK-2 is a homeodomain protein essential for the development of the central nervous system in the Drosophila embryo. Here, we show that the vnd/NK-2 gene encodes an additional protein isoform (NK-2B) that differs from the known one (NK-2A) in its N-terminal domain. While NK-2A is a transcription repr...
Autores principales: | Stepchenko, Alexander G., Pankratova, Elizaveta V., Doronin, Semen A., Gulag, Pavel V., Georgieva, Sofia G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141242/ https://www.ncbi.nlm.nih.gov/pubmed/21422076 http://dx.doi.org/10.1093/nar/gkr121 |
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