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Analysis of microRNA turnover in mammalian cells following Dicer1 ablation

Although microRNAs (miRNAs) are key regulators of gene expression, little is known of their overall persistence in the cell following processing. Characterization of such persistence is key to the full appreciation of their regulatory roles. Accordingly, we measured miRNA decay rates in mouse embryo...

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Detalles Bibliográficos
Autores principales: Gantier, Michael P., McCoy, Claire E., Rusinova, Irina, Saulep, Damien, Wang, Die, Xu, Dakang, Irving, Aaron T., Behlke, Mark A., Hertzog, Paul J., Mackay, Fabienne, Williams, Bryan R. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141258/
https://www.ncbi.nlm.nih.gov/pubmed/21447562
http://dx.doi.org/10.1093/nar/gkr148