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Analysis of microRNA turnover in mammalian cells following Dicer1 ablation
Although microRNAs (miRNAs) are key regulators of gene expression, little is known of their overall persistence in the cell following processing. Characterization of such persistence is key to the full appreciation of their regulatory roles. Accordingly, we measured miRNA decay rates in mouse embryo...
Autores principales: | Gantier, Michael P., McCoy, Claire E., Rusinova, Irina, Saulep, Damien, Wang, Die, Xu, Dakang, Irving, Aaron T., Behlke, Mark A., Hertzog, Paul J., Mackay, Fabienne, Williams, Bryan R. G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141258/ https://www.ncbi.nlm.nih.gov/pubmed/21447562 http://dx.doi.org/10.1093/nar/gkr148 |
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