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Assembly of custom TALE-type DNA binding domains by modular cloning

Transcription activator-like effector (TALE) DNA binding proteins show tremendous potential as molecular tools for targeted binding to any desired DNA sequence. Their DNA binding domain consists of tandem arranged repeats, and due to this repetitive structure it is challenging to generate designer T...

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Detalles Bibliográficos
Autores principales: Morbitzer, Robert, Elsaesser, Janett, Hausner, Jens, Lahaye, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141260/
https://www.ncbi.nlm.nih.gov/pubmed/21421566
http://dx.doi.org/10.1093/nar/gkr151