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Assembly of custom TALE-type DNA binding domains by modular cloning
Transcription activator-like effector (TALE) DNA binding proteins show tremendous potential as molecular tools for targeted binding to any desired DNA sequence. Their DNA binding domain consists of tandem arranged repeats, and due to this repetitive structure it is challenging to generate designer T...
Autores principales: | Morbitzer, Robert, Elsaesser, Janett, Hausner, Jens, Lahaye, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141260/ https://www.ncbi.nlm.nih.gov/pubmed/21421566 http://dx.doi.org/10.1093/nar/gkr151 |
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