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Evolutionary expansion of the Ras switch regulatory module in eukaryotes

Ras proteins control many aspects of eukaryotic cell homeostasis by switching between active (GTP-bound) and inactive (GDP-bound) conformations, a reaction catalyzed by GTPase exchange factors (GEF) and GTPase activating proteins (GAP) regulators, respectively. Here, we show that the complexity, mea...

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Detalles Bibliográficos
Autores principales: Díez, Diego, Sánchez-Jiménez, Francisca, Ranea, Juan A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141262/
https://www.ncbi.nlm.nih.gov/pubmed/21447561
http://dx.doi.org/10.1093/nar/gkr154