Translational and transcriptional control of Sp1 against ischaemia through a hydrogen peroxide-activated internal ribosomal entry site pathway

The exact mechanism underlying increases in Sp1 and the physiological consequences thereafter remains unknown. In rat primary cortical neurons, oxygen-glucose deprivation (OGD) causes an increase in H(2)O(2) as well as Sp1 in early ischaemia but apparently does not change mRNA level or Sp1 stability...

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Detalles Bibliográficos
Autores principales: Yeh, Shiu Hwa, Yang, Wen Bin, Gean, Po Wu, Hsu, Chung Yi, Tseng, Joseph T., Su, Tsung Ping, Chang, Wen Chang, Hung, Jan Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141265/
https://www.ncbi.nlm.nih.gov/pubmed/21441538
http://dx.doi.org/10.1093/nar/gkr161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141265/
https://www.ncbi.nlm.nih.gov/pubmed/21441538
http://dx.doi.org/10.1093/nar/gkr161

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