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Optimizing HIV-1 protease production in Escherichia coli as fusion protein

BACKGROUND: Human immunodeficiency virus (HIV) is the etiological agent in AIDS and related diseases. The aspartyl protease encoded by the 5' portion of the pol gene is responsible for proteolytic processing of the gag-pol polyprotein precursor to yield the mature capsid protein and the reverse...

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Detalles Bibliográficos
Autores principales: Volontè, Federica, Piubelli, Luciano, Pollegioni, Loredano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141379/
https://www.ncbi.nlm.nih.gov/pubmed/21718537
http://dx.doi.org/10.1186/1475-2859-10-53