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Molecular role of GATA binding protein 4 (GATA-4) in hyperglycemia-induced reduction of cardiac contractility

BACKGROUND: Diabetic cardiomyopathy, a diabetes-specific complication, refers to a disorder that eventually leads to left ventricular hypertrophy in addition to diastolic and systolic dysfunction. In recent studies, hyperglycemia-induced reactive oxygen species (ROS) in cardiomyocytes have been link...

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Detalles Bibliográficos
Autores principales: Ku, Po-Ming, Chen, Li-Jen, Liang, Jia-ru, Cheng, Kai-Chun, Li, Yin-Xiao, Cheng, Juei-Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141394/
https://www.ncbi.nlm.nih.gov/pubmed/21702924
http://dx.doi.org/10.1186/1475-2840-10-57