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Intrathecal lidocaine pretreatment attenuates immediate neuropathic pain by modulating Nav(1.3 )expression and decreasing spinal microglial activation

BACKGROUND: Intrathecal lidocaine reverses tactile allodynia after nerve injury, but whether neuropathic pain is attenuated by intrathecal lidocaine pretreatment is uncertain. METHODS: Sixty six adult male Sprague-Dawley rats were divided into three treatment groups: (1) sham (Group S), which underw...

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Detalles Bibliográficos
Autores principales:	Cheng, Kuang-I, Lai, Chung-Sheng, Wang, Fu-Yuan, Wang, Hung-Chen, Chang, Lin-Li, Ho, Shung-Tai, Tsai, Hung-Pei, Kwan, Aij-Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141398/ https://www.ncbi.nlm.nih.gov/pubmed/21676267 http://dx.doi.org/10.1186/1471-2377-11-71

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