Cargando…

Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertension

BACKGROUND: Endothelin-1 signalling plays an important role in pathogenesis of pulmonary hypertension. Although different endothelin-A receptor antagonists are developed, a novel therapeutic option to cure the disease is still needed. This study aims to investigate the therapeutic efficacy of the se...

Descripción completa

Detalles Bibliográficos
Autores principales: Kosanovic, Djuro, Kojonazarov, Baktybek, Luitel, Himal, Dahal, Bhola K, Sydykov, Akylbek, Cornitescu, Teodora, Janssen, Wiebke, Brandes, Ralf P, Davie, Neil, Ghofrani, Hossein A, Weissmann, Norbert, Grimminger, Friedrich, Seeger, Werner, Schermuly, Ralph T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141422/
https://www.ncbi.nlm.nih.gov/pubmed/21699729
http://dx.doi.org/10.1186/1465-9921-12-87