Increased local concentration of complement C5a contributes to incisional pain in mice

BACKGROUND: In our previous study, we demonstrated that local injection of complement C5a and C3a produce mechanical and heat hyperalgesia, and that C5a and C3a activate and sensitize cutaneous nociceptors in normal skin, suggesting a contribution of complement fragments to acute pain. Other studies...

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Detalles Bibliográficos
Autores principales: Jang, Jun H, Liang, Deyong, Kido, Kanta, Sun, Yuan, Clark, David J, Brennan, Timothy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141504/
https://www.ncbi.nlm.nih.gov/pubmed/21736743
http://dx.doi.org/10.1186/1742-2094-8-80

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141504/
https://www.ncbi.nlm.nih.gov/pubmed/21736743
http://dx.doi.org/10.1186/1742-2094-8-80

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