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Oxymatrine induces human pancreatic cancer PANC-1 cells apoptosis via regulating expression of Bcl-2 and IAP families, and releasing of cytochrome c

BACKGROUND: Oxymatrine, an isolated extract from traditional Chinese herb Sophora Flavescens Ait, has been traditionally used for therapy of anti-hepatitis B virus, anti-inflammation and anti-anaphylaxis. The present study was to investigate the anti-cancer effect of oxymatrine on human pancreatic c...

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Detalles Bibliográficos
Autores principales: Ling, Qi, Xu, Xiao, Wei, Xuyong, Wang, Weibing, Zhou, Bin, Wang, Bei, Zheng, Shusen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141557/
https://www.ncbi.nlm.nih.gov/pubmed/21714853
http://dx.doi.org/10.1186/1756-9966-30-66