An untargeted multi-technique metabolomics approach to studying intracellular metabolites of HepG2 cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin

BACKGROUND: In vitro cell systems together with omics methods represent promising alternatives to conventional animal models for toxicity testing. Transcriptomic and proteomic approaches have been widely applied in vitro but relatively few studies have used metabolomics. Therefore, the goal of the p...

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Detalles Bibliográficos
Autores principales: Ruiz-Aracama, Ainhoa, Peijnenburg, Ad, Kleinjans, Jos, Jennen, Danyel, van Delft, Joost, Hellfrisch, Caroline, Lommen, Arjen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141663/
https://www.ncbi.nlm.nih.gov/pubmed/21599895
http://dx.doi.org/10.1186/1471-2164-12-251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141663/
https://www.ncbi.nlm.nih.gov/pubmed/21599895
http://dx.doi.org/10.1186/1471-2164-12-251

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