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RNA-seq: technical variability and sampling

BACKGROUND: RNA-seq is revolutionizing the way we study transcriptomes. mRNA can be surveyed without prior knowledge of gene transcripts. Alternative splicing of transcript isoforms and the identification of previously unknown exons are being reported. Initial reports of differences in exon usage, a...

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Detalles Bibliográficos
Autores principales: McIntyre, Lauren M, Lopiano, Kenneth K, Morse, Alison M, Amin, Victor, Oberg, Ann L, Young, Linda J, Nuzhdin, Sergey V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141664/
https://www.ncbi.nlm.nih.gov/pubmed/21645359
http://dx.doi.org/10.1186/1471-2164-12-293