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Renal cell carcinoma primary cultures maintain genomic and phenotypic profile of parental tumor tissues

BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is characterized by recurrent copy number alterations (CNAs) and loss of heterozygosity (LOH), which may have potential diagnostic and prognostic applications. Here, we explored whether ccRCC primary cultures, established from surgical tumor specim...

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Detalles Bibliográficos
Autores principales: Cifola, Ingrid, Bianchi, Cristina, Mangano, Eleonora, Bombelli, Silvia, Frascati, Fabio, Fasoli, Ester, Ferrero, Stefano, Di Stefano, Vitalba, Zipeto, Maria A, Magni, Fulvio, Signorini, Stefano, Battaglia, Cristina, Perego, Roberto A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141767/
https://www.ncbi.nlm.nih.gov/pubmed/21668985
http://dx.doi.org/10.1186/1471-2407-11-244