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c-Myc activates BRCA1 gene expression through distal promoter elements in breast cancer cells
BACKGROUND: The BRCA1 gene plays an important role in the maintenance of genomic stability. BRCA1 inactivation contributes to breast cancer tumorigenesis. An increasing number of transcription factors have been shown to regulate BRCA1 expression. c-Myc can act as a transcriptional activator, regulat...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141769/ https://www.ncbi.nlm.nih.gov/pubmed/21668996 http://dx.doi.org/10.1186/1471-2407-11-246 |