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c-Myc activates BRCA1 gene expression through distal promoter elements in breast cancer cells

BACKGROUND: The BRCA1 gene plays an important role in the maintenance of genomic stability. BRCA1 inactivation contributes to breast cancer tumorigenesis. An increasing number of transcription factors have been shown to regulate BRCA1 expression. c-Myc can act as a transcriptional activator, regulat...

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Detalles Bibliográficos
Autores principales:	Chen, Yinghua, Xu, Jinhua, Borowicz, Stanley, Collins, Cindy, Huo, Dezheng, Olopade, Olufunmilayo I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141769/ https://www.ncbi.nlm.nih.gov/pubmed/21668996 http://dx.doi.org/10.1186/1471-2407-11-246

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